is glp 1 safe for kidney disease GLP-1 Receptor Agonists and Protection The cardiovascular and renal effects

In the Diabetes Prevention Program Outcomes Study (DPPOS, N=1,800), metformin use for a mean of 12.7 years was associated with a 13% prevalence of B12 deficiency versus 5.4% in the placebo group (P 9%) impairs wound healing regardless of peptide use [4]

doi: 10.1016/j.jaad.2008.11.009

By improving local and general blood flow, the peptide is posited to exert stomach cell protection against ischemia and damaging agents, therefore facilitating gastrointestinal tract healing

Disease-Modifying Perspective: These data support reconceptualising GLP-1RAs not merely as weight-management agents, but as cardiovascular disease-modifying therapies with pleiotropic mechanisms of action